作者: Persephone Borrow , Nina Bhardwaj
DOI: 10.1097/COH.0B013E3282F2BCE7
关键词: Disease pathogenesis 、 Human immunodeficiency virus (HIV) 、 Adaptive response 、 Innate immune system 、 Immunology 、 Viral replication 、 Medicine 、 First line 、 Disease course
摘要: Purpose of review Events occurring in acute HIV-1 infection are now recognized to be critical determinants the subsequent disease course. Innate responses constitute first line defence against pathogens, and also play a key role triggering early adaptive response; as such, innate activated their contribution control viral replication or pathogenesis focus much current research. We review recent advances this area.