作者: Carol Tan , Fergus Gleeson , Tom Treasure , None
关键词: Pemetrexed 、 Surgery 、 Mesothelioma 、 Medicine 、 Pleural effusion 、 Malignant pleural effusion 、 General surgery 、 Extrapleural Pneumonectomy 、 Pleural disease 、 Radiation therapy 、 Clinical trial
摘要: Malignant pleural mesothelioma (MPM) is a deadly disease that occurs in 2,000 to 3,000 people each year the United States. Although MPM an extremely difficult treat, with median overall survival ranging between 9 and 17 months regardless of stage, there has been significant progress over last few years reshaped clinical landscape. This article will provide comprehensive discussion latest developments treatment MPM. We update major trials impact resectable unresectable settings, discuss novel therapeutics, perspective on where research moving. In addition, are controversial issues, such as role extrapleural pneumonectomy, adjuvant radiotherapy, use intensity-modulated radiotherapy versus hemithoracic therapy also be addressed this manuscript.