Malignant Pleural Mesothelioma

作者: Carol Tan , Fergus Gleeson , Tom Treasure , None

DOI: 10.1200/JCO.2008.19.8523

关键词: PemetrexedSurgeryMesotheliomaMedicinePleural effusionMalignant pleural effusionGeneral surgeryExtrapleural PneumonectomyPleural diseaseRadiation therapyClinical trial

摘要: Malignant pleural mesothelioma (MPM) is a deadly disease that occurs in 2,000 to 3,000 people each year the United States. Although MPM an extremely difficult treat, with median overall survival ranging between 9 and 17 months regardless of stage, there has been significant progress over last few years reshaped clinical landscape. This article will provide comprehensive discussion latest developments treatment MPM. We update major trials impact resectable unresectable settings, discuss novel therapeutics, perspective on where research moving. In addition, are controversial issues, such as role extrapleural pneumonectomy, adjuvant radiotherapy, use intensity-modulated radiotherapy versus hemithoracic therapy also be addressed this manuscript.

参考文章(548)
King Ja, Tucker Ja, Evaluation of membranous staining of mesothelioma. Cell vision : the journal of analytical morphology. ,vol. 5, pp. 24- ,(1998)
Jens Benn Sørensen, Stein Sundstrøm, Katharina Perell, Anne-Kathrine Thielsen, Pemetrexed as Second-Line Treatment in Malignant Pleural Mesothelioma after Platinum-Based First-Line Treatment Journal of Thoracic Oncology. ,vol. 2, pp. 147- 152 ,(2007) , 10.1097/JTO.0B013E31802F3813
Grace Y Ma, David L Bartlett, E Reed, William D Figg, Richard M Lush, K B Lee, Steven K Libutti, H Richard Alexander, Continuous hyperthermic peritoneal perfusion with cisplatin for the treatment of peritoneal mesothelioma The cancer journal from Scientific American. ,vol. 3, pp. 174- 179 ,(1997)
Marc Noppen, Jacques Degreve, Michael Mignolet, Walter Vincken., A prospective, randomised study comparing the efficacy of talc slurry and bleomycin in the treatment of malignant pleural effusions. Acta Clinica Belgica. ,vol. 52, pp. 258- 262 ,(1997) , 10.1080/17843286.1997.11718587
G. Falkson, A.G. Sandison, G. De Muelenaere, C. Sinoff, Combined doxorubicin and radiation therapy in malignant pleural mesothelioma Cancer treatment reports. ,vol. 66, pp. 1605- ,(1982)
Sheng Xiao, J. M. Corson, D. J. Sugarbaker, J. A. Fletcher, J. Vijg, Daizong Li, CODELETION OF P15 AND P16 IN PRIMARY MALIGNANT MESOTHELIOMA Oncogene. ,vol. 11, pp. 511- 515 ,(1995)
C Zuch, L Ramani, G Grandi, C Bianchi, A Brollo, L Giarelli, Latency periods in asbestos-related mesothelioma of the pleura. European Journal of Cancer Prevention. ,vol. 6, pp. 162- 166 ,(1997)
J Giesecke, P Olin, Potential exposure to SV40 in polio vaccines used in Sweden during 1957: no impact on cancer incidence rates 1960 to 1993. Developments in biological standardization. ,vol. 94, pp. 227- 233 ,(1998)
Douglas W. Henderson, Keith B. Shilkin, Darrel Whitaker, Reactive Mesothelial Hyperplasia vs Mesothelioma, Including Mesothelioma In Situ: A Brief Review American Journal of Clinical Pathology. ,vol. 110, pp. 397- 404 ,(1998) , 10.1093/AJCP/110.3.397