Effect of manual approaches with osteopathic modality on brain correlates of interoception: an fMRI study.
作者： Francesco Cerritelli , Piero Chiacchiaretta , Francesco Gambi , Mauro Gianni Perrucci , Giovanni Barassi
DOI: 10.1038/S41598-020-60253-6
关键词: Insula 、 Brain activity and meditation 、 Placebo-controlled study 、 Medicine 、 Young adult 、 Randomized controlled trial 、 Modality (human–computer interaction) 、 Magnetic resonance imaging 、 Interoception 、 Physical medicine and rehabilitation
摘要: The present randomised placebo controlled trial explored the extent to which osteopathic manipulative treatment (OMT) affects brain activity, particularly insula, during both an "interoceptive awareness" and "exteroceptive task in a sample of 32 right-handed adults with chronic Low Back Pain (CLBP) randomly assigned either OMT or sham group. Patients received 4 weekly sessions fMRI was performed at enrolment (T0), immediately after first session (T1) 1 month (T2). results revealed that produced distinct specific reduction BOLD response areas related interoception, i.e., bilateral ACC, left striatum rMFG. observed trend across three time points appears uncharacteristic. At T1, marginal increase all above-mentioned except rMFG, showed decrease response. T2, opposite: interoception (bilateral insula ACC) as well rMFG demonstrated significant decreased findings this study provide insight into effects manual therapies on activity have implications for future research field.
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sci-hub.se 参考文章(75)
Davies Jb, Fairbank Jc, O'Brien Jp, Couper J, The Oswestry low back pain disability questionnaire Physiotherapy. ,vol. 66, pp. 271- 273 ,(1980)
Anthony Chila, Comprar Foundations for Osteopathic Medicine , 3/e | Anthony Chila | 9780781766715 | Lippincott Williams & Wilkins Lippincott Williams & Wilkins. ,(2010)
Ian R. Kleckner, Jolie Baumann Wormwood, W. Kyle Simmons, Lisa Feldman Barrett, Karen S. Quigley, Methodological recommendations for a heartbeat detection‐based measure of interoceptive sensitivity Psychophysiology. ,vol. 52, pp. 1432- 1440 ,(2015) , 10.1111/PSYP.12503
Sahib S Khalsa, David Rudrauf, Justin S Feinstein, Daniel Tranel, The pathways of interoceptive awareness Nature Neuroscience. ,vol. 12, pp. 1494- 1496 ,(2009) , 10.1038/NN.2411
Gemma Modinos, Johan Ormel, André Aleman, None, Activation of Anterior Insula during Self-Reflection PLoS ONE. ,vol. 4, pp. e4618- ,(2009) , 10.1371/JOURNAL.PONE.0004618
O. Airaksinen, J. I. Brox, C. Cedraschi, J. Hildebrandt, J. Klaber-Moffett, F. Kovacs, A. F. Mannion, S. Reis, J. B. Staal, H. Ursin, G. Zanoli, , Chapter 4 European guidelines for the management of chronic nonspecific low back pain European Spine Journal. ,vol. 15, pp. s192- s300 ,(2006) , 10.1007/S00586-006-1072-1
Gang Chen, Nancy E. Adleman, Ziad S. Saad, Ellen Leibenluft, Robert W. Cox, Applications of multivariate modeling to neuroimaging group analysis: a comprehensive alternative to univariate general linear model. NeuroImage. ,vol. 99, pp. 571- 588 ,(2014) , 10.1016/J.NEUROIMAGE.2014.06.027
Javeria A. Hashmi, Marwan N. Baliki, Lejian Huang, Alex T. Baria, Souraya Torbey, Kristina M. Hermann, Thomas J. Schnitzer, A. Vania Apkarian, Shape shifting pain: chronification of back pain shifts brain representation from nociceptive to emotional circuits Brain. ,vol. 136, pp. 2751- 2768 ,(2013) , 10.1093/BRAIN/AWT211
Blas Couto, Federico Adolfi, Lucas Sedeño, Alejo Salles, Andrés Canales-Johnson, Pablo Alvarez-Abut, Indira Garcia-Cordero, Marcos Pietto, Tristan Bekinschtein, Mariano Sigman, Facundo Manes, Agustin Ibanez, Disentangling interoception: insights from focal strokes affecting the perception of external and internal milieus Frontiers in Psychology. ,vol. 6, pp. 503- 503 ,(2015) , 10.3389/FPSYG.2015.00503
H. D. Critchley, The human cortex responds to an interoceptive challenge. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 101, pp. 6333- 6334 ,(2004) , 10.1073/PNAS.0401510101