Mechanism of postural hypoxemia in asymptomatic smokers.

摘要: Ventilatory function, lung volumes, flow-volume curves, and alveolar-arterial oxygen tension gradients were measured in 24 smokers nonsmokers by standard methods. tests volumes normal both groups. As compared to nonsmokers, the had a slightly smaller residual volume functional capacity, (FRC), particularly supine position, their curves less favorable. result, forced expiratory flow rate at FRC position was significantly than nonsmokers. Alveolar-arterial while breathing room air larger more so (P < 0.01) erect position. When pure or 14 per cent breathed, identical groups; this indicates that maldistribution caused postural hypoxemia. gradients, subjects ro...