The relationship between central hemodynamics, morning blood pressure surge, glycemic control and sodium intake in patients with type 2 diabetes and essential hypertension

作者: Baris Afsar , Rengin Elsurer

DOI: 10.1016/J.DIABRES.2014.03.011

关键词: Blood pressureHemodynamicsDiabetes mellitusType 2 diabetesAlbuminuriaAmbulatory blood pressureEssential hypertensionEndocrinologyGlycemicMedicineInternal medicineCardiology

摘要: Abstract Aims The current study aimed to investigate the relationship between morning blood pressure surge (MBPS), hemodynamic parameters, glycemic control and 24-h urinary sodium excretion (USE) in patients with type 2 diabetes mellitus (T2DM). Materials methods MBPS central parameters were assessed from ambulatory measurements. In addition routine biochemistry, 24h urine collection was performed measure protein, albumin excretion. Results There 146 (38%) T2DM 238 (72%) without (control group). Patients had statistically higher compared ( P =0.004) various parameters. Additionally, regression analysis showed that being male =0.006), presence of coronary artery disease =0.023), HbA1c =0.012), USE =0.001) independently related log patients. Conclusion This demonstrated an independent risk factor for increased associated Additionally poor intake worse T2DM.

参考文章(37)
UK Prospective Diabetes Study Group, None, Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38 BMJ. ,vol. 317, pp. 703- 713 ,(1998)
M. Shimizu, J. Ishikawa, K. Eguchi, S. Hoshide, K. Shimada, K. Kario, Association of an Abnormal Blood Glucose Level and Morning Blood Pressure Surge in Elderly Subjects With Hypertension American Journal of Hypertension. ,vol. 22, pp. 611- 616 ,(2009) , 10.1038/AJH.2009.61
Minhee Suh, Debra J. Barksdale, Jeongok G. Logan, Morning Blood Pressure Surge and Nighttime Blood Pressure in Relation to Nocturnal Sleep Pattern and Arterial Stiffness The Journal of Cardiovascular Nursing. ,vol. 29, pp. E10- E17 ,(2014) , 10.1097/JCN.0B013E318291EE43
E. M. V. de Cavanagh, L. F. Ferder, M. D. Ferder, I. Y. Stella, J. E. Toblli, F. Inserra, Vascular Structure and Oxidative Stress in Salt-Loaded Spontaneously Hypertensive Rats: Effects of Losartan and Atenolol American Journal of Hypertension. ,vol. 23, pp. 1318- 1325 ,(2010) , 10.1038/AJH.2010.167
Sarah-Jane Guild, Fiona D. McBryde, Simon C. Malpas, Carolyn J. Barrett, High Dietary Salt and Angiotensin II Chronically Increase Renal Sympathetic Nerve Activity: A Direct Telemetric Study Hypertension. ,vol. 59, pp. 614- 620 ,(2012) , 10.1161/HYPERTENSIONAHA.111.180885
M. Viigimaa, B. Waeber, B. Williams, J. L. Zamorano, , , , , G. Mancia, G. De Backer, A. Dominiczak, R. Cifkova, R. Fagard, G. Germano, G. Grassi, A. M. Heagerty, S. E. Kjeldsen, S. Laurent, K. Narkiewicz, L. Ruilope, A. Rynkiewicz, R. E. Schmieder, H. A.J. Struijker Boudier, A. Zanchetti, A. Vahanian, J. Camm, R. De Caterina, V. Dean, K. Dickstein, G. Filippatos, C. Funck-Brentano, I. Hellemans, S. D. Kristensen, K. McGregor, U. Sechtem, S. Silber, M. Tendera, P. Widimsky, J. L. Zamorano, S. E. Kjeldsen, S. Erdine, K. Narkiewicz, W. Kiowski, E. Agabiti-Rosei, E. Ambrosioni, R. Cifkova, A. Dominiczak, R. Fagard, A. M. Heagerty, S. Laurent, L. H. Lindholm, G. Mancia, A. Manolis, P. M. Nilsson, J. Redon, R. E. Schmieder, H. A.J. Struijker-Boudier, M. Viigimaa, G. Filippatos, S. Adamopoulos, E. Agabiti-Rosei, E. Ambrosioni, V. Bertomeu, D. Clement, S. Erdine, C. Farsang, D. Gaita, W. Kiowski, G. Lip, J.-M. Mallion, A. J. Manolis, P. M. Nilsson, E. O'Brien, P. Ponikowski, J. Redon, F. Ruschitzka, J. Tamargo, P. van Zwieten, 2007 Guidelines for the management of arterial hypertension European Heart Journal. ,vol. 28, pp. 1462- 1536 ,(2007) , 10.1093/EURHEARTJ/EHM236
Sungha Park, Jeong B. Park, Edward G. Lakatta, Association of central hemodynamics with estimated 24-h urinary sodium in patients with hypertension. Journal of Hypertension. ,vol. 29, pp. 1502- 1507 ,(2011) , 10.1097/HJH.0B013E3283486311
S Wassertheurer, J Kropf, T Weber, M van der Giet, J Baulmann, M Ammer, B Hametner, C C Mayer, B Eber, D Magometschnigg, A new oscillometric method for pulse wave analysis: comparison with a common tonometric method. Journal of Human Hypertension. ,vol. 24, pp. 498- 504 ,(2010) , 10.1038/JHH.2010.27
Wolfgang Wei, Markus Tölle, Walter Zidek, Markus van der Giet, Validation of the mobil-O-Graph: 24 h-blood pressure measurement device. Blood Pressure Monitoring. ,vol. 15, pp. 225- 228 ,(2010) , 10.1097/MBP.0B013E328338892F
Mei-Yeh Wang, Chun-Jen Huang, Nei-Chung Chang, Pei-Shan Tsai, Reproducibility of morning blood pressure surge and its relation to blood pressure reactivity. Clinical and Experimental Hypertension. ,vol. 29, pp. 357- 368 ,(2007) , 10.1080/10641960701578345