Development and evaluation of the automated risk assessment system for multidrug-resistant organisms (autoRAS-MDRO).

作者: E.Y. Hur , Y.J. Jin , T.X. Jin , S.M. Lee

DOI: 10.1016/J.JHIN.2017.08.004

关键词: MedicinePredictive validityLogistic regressionYouden's J statisticRisk assessmentPatient safetyMultiple drug resistanceIncidence (epidemiology)Infection controlEmergency medicine

摘要: Summary Background A high proportion of infections acquired in hospitals are caused by multidrug-resistant organisms (MDROs). The priority MDRO prevention is to detect high-risk patients and implement preventive intervention as soon possible. Aim To develop an automated risk assessment system for MDROs (autoRAS-MDRO) screen at infection evaluate the predictive validity autoRAS-MDRO. Methods Data 4200 variables were extracted from electronic health records (EHRs) constructing risk-scoring algorithm, which was based on a logistic regression model. autoRAS-MDRO designed such that classification (high, moderate, low risk) could be automatically displayed nursing Kardex EHRs system. For development 1000 with 4000 without selected; similarly, evaluation, 2173 8692 MDROs, respectively, selected. Findings follows: (i) 6-month evaluation: sensitivity, 81%; specificity, 79%; positive value (PPV), 49%; negative (NPV), 94%; Youden index, 0.60; (ii) 12-month sensitivity 79%, specificity 78%, PPV 47%, NPV 94%, 0.57. Conclusion had moderate validity. It useful redirecting nurses’ time efforts required implementation control measures, reducing incidence hospitals, thereby contributing patient safety.

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