Fluid dynamics model of mitral valve flow: Description with in vitro validation
作者： James D. Thomas , Arthur E. Weyman
DOI: 10.1016/0735-1097(89)90575-5
关键词: Blood flow 、 Internal medicine 、 Compliance (physiology) 、 Mitral valve 、 Doppler echocardiography 、 Medicine 、 Pressure gradient 、 Cardiology 、 Stenosis 、 Hemodynamics 、 Ventricular pressure 、 Cardiology and Cardiovascular Medicine
摘要: A lumped variable fluid dynamics model of mitral valve blood flow is described that applicable to both Doppler echocardiography and invasive hemodynamic measurement. Given left atrial ventricular compliance, initial pressures impedance, the predicts time course pressure. The predictions this mathematic formulation have been tested in an vitro analog heart which area compliance can be accurately controlled. For situation constant chamber transmitral gradient predicted decay as a parabolic curve, has confirmed with r greater than 0.99 all cases for range orifice from 0.3 3.0 cm2, pressure 2.4 14.2 mm Hg net 16 29 cc/mm Hg. This should help unify echocardiographic catheterization assessment stenosis diastolic dysfunction.
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