Fractionation of protein mixtures
作者： Surendar M. Jain
DOI:
关键词: Globulin 、 Chromatography 、 Centrifugation 、 Fractionation 、 Antihemophilic factor 、 Filtration 、 Electrolyte 、 Chemistry 、 Therapeutic plasma exchange 、 Electrodialysis
摘要: This invention relates to the separation of complex protein mixtures by lowering (desalting) or raising (salting-out) their electrolytic (ionic) concentration electrodialysis followed chilling, pH adjustment, filtration, and/or centrifugation and optionally thereafter restoration lost electrolyte removal gained water. technique is especially adaptable for therapeutic plasma exchange performed in situ immunepheresis i.e. globulin immunecomplexes implicated autoimmune diseases. The techniques are also applicable antihemophilic factor purification, proteins from whey.
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