PINK1/Parkin-mediated mitophagy in mammalian cells.

作者: Akinori Eiyama , Koji Okamoto

DOI: 10.1016/J.CEB.2015.01.002

关键词: UbiquitinPINK1MitophagyCell biologyBiologyMitochondrionAutophagyUbiquitin ligaseDeubiquitinationParkin

摘要: … is partially translocated across the mitochondrial membranes … -anchored PINK1 variant can recruit Parkin to peroxisomes … for depolarized mitochondria revealed that mitochondrial …

参考文章(61)
Cathrin Meissner, Holger Lorenz, Andreas Weihofen, Dennis J. Selkoe, Marius K. Lemberg, The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking Journal of Neurochemistry. ,vol. 117, pp. 856- 867 ,(2011) , 10.1111/J.1471-4159.2011.07253.X
Tohru Kitada, Shuichi Asakawa, Nobutaka Hattori, Hiroto Matsumine, Yasuhiro Yamamura, Shinsei Minoshima, Masayuki Yokochi, Yoshikuni Mizuno, Nobuyoshi Shimizu, Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism Nature. ,vol. 392, pp. 605- 608 ,(1998) , 10.1038/33416
Elena I Rugarli, Thomas Langer, Mitochondrial quality control: a matter of life and death for neurons The EMBO Journal. ,vol. 31, pp. 1336- 1349 ,(2012) , 10.1038/EMBOJ.2012.38
Koji Okamoto, Organellophagy: Eliminating cellular building blocks via selective autophagy Journal of Cell Biology. ,vol. 205, pp. 435- 445 ,(2014) , 10.1083/JCB.201402054
Kahori Shiba-Fukushima, Taku Arano, Gen Matsumoto, Tsuyoshi Inoshita, Shigeharu Yoshida, Yasushi Ishihama, Kwon-Yul Ryu, Nobuyuki Nukina, Nobutaka Hattori, Yuzuru Imai, Phosphorylation of Mitochondrial Polyubiquitin by PINK1 Promotes Parkin Mitochondrial Tethering PLoS Genetics. ,vol. 10, pp. e1004861- ,(2014) , 10.1371/JOURNAL.PGEN.1004861
Victoria S Burchell, David E Nelson, Alvaro Sanchez-Martinez, Marta Delgado-Camprubi, Rachael M Ivatt, Joe H Pogson, Suzanne J Randle, Selina Wray, Patrick A Lewis, Henry Houlden, Andrey Y Abramov, John Hardy, Nicholas W Wood, Alexander J Whitworth, Heike Laman, Helene Plun-Favreau, The Parkinson's disease–linked proteins Fbxo7 and Parkin interact to mediate mitophagy Nature Neuroscience. ,vol. 16, pp. 1257- 1265 ,(2013) , 10.1038/NN.3489
Valerie Lefebvre, Qiujiang Du, Stephen Baird, Andy Cheuk-Him Ng, Mirna Nascimento, Michelangelo Campanella, Heidi M McBride, Robert A Screaton, Genome-wide RNAi screen identifies ATPase inhibitory factor 1 (ATPIF1) as essential for PARK2 recruitment and mitophagy Autophagy. ,vol. 9, pp. 1770- 1779 ,(2013) , 10.4161/AUTO.25413
Sumihiro Kawajiri, Shinji Saiki, Shigeto Sato, Fumiaki Sato, Taku Hatano, Hiroto Eguchi, Nobutaka Hattori, PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy FEBS Letters. ,vol. 584, pp. 1073- 1079 ,(2010) , 10.1016/J.FEBSLET.2010.02.016
Emilie Hollville, Richard G. Carroll, Sean P. Cullen, Seamus J. Martin, Bcl-2 Family Proteins Participate in Mitochondrial Quality Control by Regulating Parkin/PINK1-Dependent Mitophagy Molecular Cell. ,vol. 55, pp. 451- 466 ,(2014) , 10.1016/J.MOLCEL.2014.06.001
Dawn M. Wenzel, Alexei Lissounov, Peter S. Brzovic, Rachel E. Klevit, UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids Nature. ,vol. 474, pp. 105- 108 ,(2011) , 10.1038/NATURE09966