Coronary heart disease mortality/morbidity and risk in blacks. I: Clinical manifestations and diagnostic criteria: The experience with the Beta Blocker Heart Attack Trial

摘要: A comparison was made of the clinical manifestations and diagnostic criteria coronary artery disease in black nonblack patients cohort participants Beta Blocker Heart Attack Trial (BHAT). Although were uniform for all potential trial, examination baseline data indicates that had a higher proportion cardiomegaly ECGs with left ventricular hypertrophy ST-T wave changes lower percentage transmural myocardial infarction to patients. Baseline also show blacks, nonblacks, variables shown be characteristic high-risk group, including current smoking status, rapid heart rate, angina, high blood pressure, elevated cholesterol, diuretic use, vasodilator use. The Cox regression analysis confirmed positive association these risk descriptors outcome overall study. Walker-Duncan multivariate ascribed significance nonblacks only. Blacks (n = 333) placebo treatment mortality rates 15.9 11.7, compared 9.8 7.2, respectively, study 3837). Thus reduction among blacks who received propranolol after recent comparable other groups BHAT.