作者: David A. Fruman , Honyin Chiu , Benjamin D. Hopkins , Shubha Bagrodia , Lewis C. Cantley
DOI: 10.1016/J.CELL.2017.07.029
关键词: Disease 、 Function (biology) 、 Idelalisib 、 Biology 、 Immune system 、 Cancer 、 Immunology 、 Bioinformatics 、 Signal transduction 、 Growth factor receptor 、 PI3K/AKT/mTOR pathway 、 General Biochemistry, Genetics and Molecular Biology
摘要: … (PI3K) activity is stimulated by diverse oncogenes and growth factor receptors, and elevated PI3K … We also discuss recent progress developing PI3K-targeted therapies for treatment of …