An Overview of Antiviral RNA Silencing in Plant: Biogenesis, Host-Virus Interaction and Potential Applications

摘要: Small RNA molecules play a crucial regulatory role in maintaining genome stability as well developmental regulations through set of complex and partially overlapping pathways wide range eukaryotic organisms. Active both cytoplasm nucleus, interference regulates gene expression transcriptional repression by epigenetic modification interaction with transcription machinery. interfering RNAs (siRNAs/miRNAs) 21–24 nucleotides constitute the innate defence arm against variety pathogens, especially viruses. Plant viruses either DNA or genomes are subjected to small RNA-directed degradation. Additionally, another line ‘RNA-directed methylations’ (RdDM). On other hand, viral-encoded proteins, called silencing suppressors (VSRs), known counter machinery, therefore virus can evade host surveillance system. Some plant additionally adopt certain strategies like acquiring resistant structures (some virus) machinery thereby shaping viral genome. Recently, it has been reported that particular proteins siRNAs contribute directly pathogenicity interacting RNAs. Transcriptional regulation origin plays important pathogenesis symptom development. cellular rather than pathogen have also found broad improving basal case plant–virus interaction. This chapter provides key insights into intricate diverse mechanisms, describes various evolutionary at steps, offers broader view recovery following infection finally suggests possible applications generate plants.