Hypothalamic effects on spinal reflexes and their alteration by pentobarbital

摘要: Abstract The effects of hypothalamic stimulation on spinal cord reflexes were investigated in intact, immobilized cats and animals under different levels pentobarbital anesthesia. Concurrently, potentials evoked the hypothalamus upon peripheral studied. In lightly anesthetized animals, high-frequency usually potentiated monosynaptic depressed polysynaptic reflexes. effect former was much more consistent reliable. these nerve 20- to 40-msec latency. Moderate anesthesia caused diminution reflexes, disappearance peripherally hypothalamus. Deepening abolished facilitation reflex. Hypothalamic had little or no response those which it persisted. At this stage deep anesthesia, high-voltage secondary long latency (60–160 msec) stimulation. Although mechanisms may account for part observed results, data indicate that noted are due primarily actions It is postulated intact animal facilitatory brain-stem regions have a predominant (or decerebration) attenuates effect, thus allowing inhibitory bulbar reticular formation be shown.