Metagenomic analysis reveals linkages between cecal microbiota and feed efficiency in Xiayan chickens.

摘要: Abstract The cecal microbiota plays a critical role in energy harvest and nutrient digestion, influencing intestinal health the performance of chickens. Feed efficiency (FE) is essential for improving economic saving social resources chicken production may be affected by microbiota. Therefore, to investigate composition functional capacity cecum microbes related FE Xiayan chicken, an indigenous breed Guangxi province, metagenome sequencing was performed on contents. 173 male 167 female chickens were divided into high low groups according residual feed intake. microbial genome extracted sequenced. results showed that genera Bacteroides, Prevotella, Alistipes 3 most abundant each microbiome. linear discriminant analysis effect size revealed 6 potential biomarkers 14 Notably, relative abundance Lactobacillus group higher than both chickens, species Limosilactobacillus oris has score In contrast, some potentially pathogenic microorganisms such as Campylobacter avium females Helicobacter pullorum males enriched group. Predictive had greater ability xenobiotics biodegradation metabolism signaling molecules interaction. addition, host sex found exert effects function associated with FE. These increased our understanding identified many FE, which used improve