Pulmonary Insufficiency: Advantage of Pulmonary Regurgitation Volume Versus Pulmonary Regurgitation Fraction in a Congenital Heart Disease Mixed Population.

作者: Francesco Secchi , Massimo Chessa , Marcello Petrini , Caterina B. Monti , Marco Alì

DOI: 10.1097/RTI.0000000000000400

关键词: Internal medicinePopulationMedicinePulmonary heart diseasePulmonary insufficiencyHeart diseaseTetralogy of FallotStroke volumeDiastoleCardiologyEjection fraction

摘要: OBJECTIVE The objective of this study was to compare the use pulmonary regurgitation volume (PRV) or indexed PRV (PRVi) with that fraction (PRF) in assessment patients (PR) undergoing cardiac magnetic resonance (CMR) imaging. MATERIALS AND METHODS CMR 176 PR were retrospectively evaluated. Their right ventricular diastolic (end-diastolic index [EDVi]) and systolic (end-systolic index) indexes, stroke volume, ejection obtained from cine sequences, whereas phase-contrast flow sequences analyzed obtain PRV, PRVi, PRF. Patients divided into subgroups, according underlying pathology severity. Correlations between PRF RV parameters studied through Spearman ρ, both main group subgroups. Follow-up examinations analyzed, correlations first examination data second calculated. RESULTS Tetralogy Fallot setting (98/179). Overall, EDVi strongly correlates (ρ=0.592, P<0.001) than (ρ=0.522, P<0.001), end-systolic (ρ=0.454, (ρ=0.406, P <0.001). As regards subgroup analysis, moderate severe patients, (P=0.043) (ρ=0.499, (ρ=0.317, P<0.001). (ρ=0.450, P=0.031), but not CONCLUSIONS Especially when assessing PR, PRVi may be better indicators dysfunction Moreover, a predictor worsening dilation.

参考文章(24)
John J. Rommel, Pradeep K. Yadav, George A. Stouffer, Causes and hemodynamic findings in chronic severe pulmonary regurgitation. Catheterization and Cardiovascular Interventions. ,vol. 92, ,(2018) , 10.1002/CCD.26073
Frederique Bailliard, Robert H Anderson, Tetralogy of Fallot Orphanet Journal of Rare Diseases. ,vol. 4, pp. 2- 2 ,(2009) , 10.1186/1750-1172-4-2
Jonathan Kochav, Lauren Simprini, Jonathan W. Weinsaft, Imaging of the Right Heart—CT and CMR Echocardiography-a Journal of Cardiovascular Ultrasound and Allied Techniques. ,vol. 32, ,(2015) , 10.1111/ECHO.12212
F. Secchi, G. Di Leo, G.D.E. Papini, V.G. Nardella, D. Negura, M. Carminati, F. Sardanelli, Cardiac magnetic resonance: Impact on diagnosis and management of patients with congenital cardiovascular disease Clinical Radiology. ,vol. 66, pp. 720- 725 ,(2011) , 10.1016/J.CRAD.2011.03.007
Peter J. Cawley, Jeffrey H. Maki, Catherine M. Otto, Cardiovascular Magnetic Resonance Imaging for Valvular Heart Disease Technique and Validation Circulation. ,vol. 119, pp. 468- 478 ,(2009) , 10.1161/CIRCULATIONAHA.107.742486
Judith Therrien, Yves Provost, Naeem Merchant, William Williams, Jack Colman, Gary Webb, Optimal timing for pulmonary valve replacement in adults after tetralogy of Fallot repair American Journal of Cardiology. ,vol. 95, pp. 779- 782 ,(2005) , 10.1016/J.AMJCARD.2004.11.037
Richard V Williams, L LuAnn Minich, Robert E Shaddy, Luciana T Pagotto, Lloyd Y Tani, None, Comparison of Doppler echocardiography with angiography for determining the severity of pulmonary regurgitation The American Journal of Cardiology. ,vol. 89, pp. 1438- 1441 ,(2002) , 10.1016/S0002-9149(02)02365-2
Aditya K. Kaza, Hong-Gook Lim, Daniel J. Dibardino, Victor Bautista-Hernandez, Joshua Robinson, Catherine Allan, Peter Laussen, Francis Fynn-Thompson, Emile Bacha, Pedro J. del Nido, John E. Mayer, Frank A. Pigula, Long-term results of right ventricular outflow tract reconstruction in neonatal cardiac surgery: options and outcomes. The Journal of Thoracic and Cardiovascular Surgery. ,vol. 138, pp. 911- 916 ,(2009) , 10.1016/J.JTCVS.2008.10.058
R. M. Wald, A. N. Redington, A. Pereira, Y. L. Provost, N. S. Paul, E. N. Oechslin, C. K. Silversides, Refining the assessment of pulmonary regurgitation in adults after tetralogy of Fallot repair: should we be measuring regurgitant fraction or regurgitant volume? European Heart Journal. ,vol. 30, pp. 356- 361 ,(2008) , 10.1093/EURHEARTJ/EHN595