Knowledgeable Clustering of Microarray Data

作者: George Potamias

DOI: 10.1007/978-3-540-30547-7_49

关键词: Pattern recognitionGraph (abstract data type)Clustering high-dimensional dataHierarchical clusteringArtificial intelligenceCURE data clustering algorithmData miningCorrelation clusteringCluster analysisMinimum spanning treeSingle-linkage clusteringComputer science

摘要: A novel graph-theoretic clustering (GTC) is presented. The method relies on a weighted graph arrangement of the genes, and iterative partitioning respective minimum spanning tree graph. final result hierarchical genes. GTC utilizes information about functional classification genes to knowledgeably guide process achieve more informative results. was applied tested an indicative real-world domain producing satisfactory biologically valid Future R&D directions are also posted.

参考文章(12)
Llanos Mora López, Inmaculada Fortes Ruiz, Rafael Morales Bueno, Francisco Triguero Ruiz, Dynamic Discretization of Continuous Values from Time Series european conference on machine learning. pp. 280- 291 ,(2000) , 10.1007/3-540-45164-1_30
Harpreet S. Sawhney, King-Ip Lin, Kyuseok Shim, Rakesh Agrawal, Fast Similarity Search in the Presence of Noise, Scaling, and Translation in Time-Series Databases very large data bases. pp. 490- 501 ,(1995)
E.C. Pielou, The measurement of diversity in different types of biological collections Journal of Theoretical Biology. ,vol. 13, pp. 131- 144 ,(1966) , 10.1016/0022-5193(66)90013-0
R. C. Prim, Shortest Connection Networks And Some Generalizations Bell System Technical Journal. ,vol. 36, pp. 1389- 1401 ,(1957) , 10.1002/J.1538-7305.1957.TB01515.X
Mark Schena, Renu A Heller, Thomas P Theriault, Ken Konrad, Eric Lachenmeier, Ronald W Davis, Microarrays: biotechnology's discovery platform for functional genomics Trends in Biotechnology. ,vol. 16, pp. 301- 306 ,(1998) , 10.1016/S0167-7799(98)01219-0
George Potamias, Catherine R. Dermon, Protein synthesis profiling in the developing brain: a graph theoretic clustering approach. Computer Methods and Programs in Biomedicine. ,vol. 76, pp. 115- 129 ,(2004) , 10.1016/J.CMPB.2004.05.002
Douglas H. Fisher, Knowledge acquisition via incremental conceptual clustering Machine Learning. ,vol. 2, pp. 139- 172 ,(1987) , 10.1023/A:1022852608280
Douglas E. Bassett, Michael B. Eisen, Mark S. Boguski, Gene expression informatics--it's all in your mine. Nature Genetics. ,vol. 21, pp. 51- 55 ,(1999) , 10.1038/4478
X. Wen, S. Fuhrman, G. S. Michaels, D. B. Carr, S. Smith, J. L. Barker, R. Somogyi, Large-scale temporal gene expression mapping of central nervous system development. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 95, pp. 334- 339 ,(1998) , 10.1073/PNAS.95.1.334