EMPA-REG OUTCOME: The Cardiologist's Point of View.

作者: Son V. Pham , Robert Chilton

DOI: 10.1016/J.AMJMED.2017.04.006

关键词: Heart failureType 2 Diabetes MellitusCompliance (physiology)Internal medicineCardiovascular physiologyCardiologyMyocardial oxygen consumptionMedicineEmpagliflozinIn patientBlood pressure

摘要: Cardiologists could view empagliflozin as a cardiovascular drug that also has beneficial effect on reducing hyperglycemia in patients with type 2 diabetes mellitus (T2DM). The effects of lowering the risk death and hospitalization for heart failure T2DM high during recent Empagliflozin Cardiovascular Outcome Event Trial Type Diabetes Mellitus Patients-Removing Excess Glucose (EMPA-REG OUTCOME) trial may be explained principally terms changes to physiology; namely, by potential ability reduce cardiac workload myocardial oxygen consumption blood pressure, improving aortic compliance, ventricular arterial coupling. These concepts hypotheses are discussed this report.

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