作者: Son V. Pham , Robert Chilton
DOI: 10.1016/J.AMJMED.2017.04.006
关键词: Heart failure 、 Type 2 Diabetes Mellitus 、 Compliance (physiology) 、 Internal medicine 、 Cardiovascular physiology 、 Cardiology 、 Myocardial oxygen consumption 、 Medicine 、 Empagliflozin 、 In patient 、 Blood pressure
摘要: Cardiologists could view empagliflozin as a cardiovascular drug that also has beneficial effect on reducing hyperglycemia in patients with type 2 diabetes mellitus (T2DM). The effects of lowering the risk death and hospitalization for heart failure T2DM high during recent Empagliflozin Cardiovascular Outcome Event Trial Type Diabetes Mellitus Patients-Removing Excess Glucose (EMPA-REG OUTCOME) trial may be explained principally terms changes to physiology; namely, by potential ability reduce cardiac workload myocardial oxygen consumption blood pressure, improving aortic compliance, ventricular arterial coupling. These concepts hypotheses are discussed this report.