Method and Composition for Treating Alzheimer's Disease and Dementias of Vascular Origin

作者: Anil Gulati

DOI:

关键词: DiseasePathologyActive agentAntagonistDementiaMedicineBioinformaticsEndothelin receptor

摘要: A composition and method of treating Alzheimer's disease or a dementia vascular origin are disclosed. The utilize an endothelin antagonist as the active agent to treat in mammals, including humans.

参考文章(24)
Zeinab Khalil, Helen Poliviou, Christa J. Maynard, Konrad Beyreuther, Colin L. Masters, Qiao-Xin Li, Mechanisms of peripheral microvascular dysfunction in transgenic mice overexpressing the Alzheimer's disease amyloid Aβ protein Journal of Alzheimer's Disease. ,vol. 4, pp. 467- 478 ,(2002) , 10.3233/JAD-2002-4603
Peter J. Harrington, Hiralal N. Khatri, Bradley S. DeHoff, Preparation of sulfonamides. ,(2000)
Michael P. Pieper, Michel Pairet, Christopher J. M. Meade, Pharmaceutical compositions based on anticholinergics and endothelin antagonists ,(2002)
Eric Jacob Watsky, Edmund Patrick Harrigan, Brian Thomas O'neill, Jotham Wadsworth Coe, Steven Bradley Sands, A pharmaceutical composition and method of treatment of diseases of cognitive dysfunction in a mammal ,(2001)
Karl Rudolphi, Hans-Peter Schubert, Hildegard Nimmesgern, Combination preparation for use in dementia ,(1998)
Tatsurou Yagami, Keiichi Ueda, Kenji Asakura, Takayuki Kuroda, Satoshi Hata, Toshiyuki Sakaeda, Yoshikazu Kambayashi, Masafumi Fujimoto, Effects of endothelin B receptor agonists on amyloid β protein (25–35)-induced neuronal cell death Brain Research. ,vol. 948, pp. 72- 81 ,(2002) , 10.1016/S0006-8993(02)02951-7