Cardiovascular disease among diabetic women with bilateral oophorectomy.

摘要: Cardiovascular Disease (CVD) is the leading cause of death in women and risk increased threefold diabetics. In postmenopausal diabetics, ovary responds to hyperinsulinemia by increasing secretion testosterone precursors which increases CVD. Data from National Health Nutrition Examination Survey (1988-2010) Study Osteoporotic Fractures were used test hypothesis that a history bilateral oophorectomy -surgical removal both ovaries-would decrease CVD among diabetic due reduced androgen levels. Logistic regression, discrete time logit model, B-Spline regression Cox proportional hazards models performed with adjusted estimates 95% confidence intervals (CIs) calculated. Overall, studies comprised 17,549 approximately 17.1 % having diabetes Mellitus. Additionally, 24.1% had undergone 55% these surgery before age 45 years. Diabetics more likely be obese, live sedentary lifestyle, have dyslipidemia report higher prevalence stroke myocardial infarction than non diabetics at baseline. Women who years nulliparous family infarction. Diabetic lower levels total compared intact ovaries or naturally menopausal non-diabetic women, was independent body mass index (p=0.016). multivariable models, predictive prevalent (Odds ratio: 1.63 (95% CI: 1.16 - 2.30) odds limited this procedure (OR: 2.11, 1.45-3.08). Although ovarian status did not influence incident 0.78, 0.56-1.09), average menopause (51 years), without observed elevated spline models. Furthermore, mortality for irrespective status, although no an (Hazard 2.57, 1.18-3.67) those (HR: 1.99, 1.65-2.39). This present analyses consisting three different population-based samples support protective effect on cardiovascular health women; however, our interpretation data often younger inherited factor heart disease.