Imaging of the Muscle-Bone Relationship

作者: Alex Ireland , José Luis Ferretti , Jörn Rittweger

DOI: 10.1007/S11914-014-0216-1

关键词: Diagnostic toolsBiomedical engineeringBone mineralSecondary osteoporosisMineral densityClinical PracticeMedicineAnatomyBone imaging

摘要: Muscle can be assessed by imaging techniques according to its size (as thickness, area, volume, or alternatively, as a mass) and architecture (fiber length pennation angle), with values used an anthropometric measure surrogate for force production. Similarly, the of bone area volume) imaged using MRI pQCT, although typically mineral mass is reported. Bone measures density, size, geometry also combined calculate bone’s structural strength—measures being highly predictive failure load ex vivo. Imaging muscle-bone relationships can, hence, accomplished through number approaches adoption comparison these different muscle parameters, dependent on research question under investigation. These have revealed evidence direct, mechanical interactions independent allometric associations. They led important information mechanoadaptation influence muscular action bone, in addition influences age, gender, exercise, disuse relationships. Such analyses produced promising diagnostic tools clinical use, such identification primary, disuse-induced, secondary osteoporosis estimation safety factors. Standardization methods required permit more reliable comparisons between studies differing modes, particular aid into widespread practice.

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