[Transdermal buprenorphine for acute postoperative pain: a systematic review].

摘要: Abstract Background and objectives Postoperative pain is still a major concern in several surgical procedures. Multimodal analgesia best for postoperative management; however, opioid therapy the main treatment after Transdermal buprenorphine partial μ-agonist widely used chronic syndromes, with limited evidence acute pain. A systematic review of studies examining transdermal management surgery was conducted. Contents Data from PubMed, Embase, The Cochrane Central Register Controlled Trials (CENTRAL), CINAHL via EBSCOhost, LILACS were reviewed, including randomized clinical trials that evaluated total pain, analgesic consumption, drug-related side effects patient satisfaction regimen. nine (615 patients) included this review. Most initiated use 6 to 48 hours before surgery, maintaining 1 28 days procedure. showed lower or similar scores, consumption comparing placebo, tramadol, celecoxib, flurbiprofen parecoxib. incidence varied between studies, most showing no increase use, except one study, which compared oral fentanyl. However, results derived an overall high unclear risk bias. Conclusions Although more are necessary, initial show seems be effective safe choice