Matrix protein gene sequence analysis of avian paramyxovirus 1 isolates obtained from pigeons.

作者: Flavia Zanetti , Marianela Rodríguez , Daniel J King , Ilaria Capua , Elisa Carrillo

DOI: 10.1023/A:1023495615729

关键词: Fusion proteinViral matrix proteinGenePopulation geneticsVirusMedical microbiologyColumbidaeNewcastle diseaseBiologyGeneticsVirology

摘要: The matrix protein gene was cloned and sequenced for several recent isolates of avian paramyxovirus type 1 (APMV-1). Specifically, from pigeons doves, members the Columbidae family were examined. APMV-1 is causative agent Newcastle disease virus associated with among a diverse number species. (NDV) have also been classified as pigeon (PPMV-1). Matrix sequences PPMV-1 clustered together group relative to other species phylogenetically. However, there or doves that grouped This indicates may be circulating distinct lineage, but these harbor NDV strains well. Of particular interest dove isolate Europe had an aberrant fusion cleavage site outlying member phylogenetically between two major groups isolates.

参考文章(28)
David Swofford, PAUP* 4.0 : Phylogenetic Analysis Using Parsimony Sinauer Associates. ,(2002)
Michael P. Cummings, MEGA (Molecular Evolutionary Genetics Analysis) Dictionary of Bioinformatics and Computational Biology. ,(2004) , 10.1002/9780471650126.DOB0421.PUB2
B Gotoh, Y Ohnishi, N M Inocencio, E Esaki, K Nakayama, P J Barr, G Thomas, Y Nagai, Mammalian subtilisin-related proteinases in cleavage activation of the paramyxovirus fusion glycoprotein: superiority of furin/PACE to PC2 or PC1/PC3. Journal of Virology. ,vol. 66, pp. 6391- 6397 ,(1992) , 10.1128/JVI.66.11.6391-6397.1992
M. S. Collins, I. Strong, D. J. Alexander, Evaluation of the molecular basis of pathogenicity of the variant Newcastle disease viruses termed “pigeon PMV-1 viruses” Archives of Virology. ,vol. 134, pp. 403- 411 ,(1994) , 10.1007/BF01310577
E.F. Kaleta, D.J. Alexander, P.H. Russell, The first isolation of the avian PMV-1 virus responsible for the current panzootic in pigeons ? Avian Pathology. ,vol. 14, pp. 553- 557 ,(1985) , 10.1080/03079458508436258