作者: Peruvumba Narayan Jayakumar , Hoskote S. Chandrashekar , Shehanaz Ellika
DOI: 10.1016/B978-0-444-53490-3.00004-2
关键词: Pathology 、 Neuroimaging 、 Central nervous system 、 Brain biopsy 、 Parenchyma 、 In vivo magnetic resonance spectroscopy 、 Perfusion scanning 、 Calcification 、 Biology 、 Radiology 、 Gliosis
摘要: Abstract Parasitic infections of the central nervous system (CNS) have increased over last couple decades, partly due to a drop in living conditions large populations world and AIDS epidemic. CNS are indolent often life threatening, hence, an early diagnosis is imperative. While brain biopsy laboratory analysis remain gold standard for diagnosis, neuroimaging contributes significantly follow-up. Imaging can demonstrate extent infection complications possibly, type parasitic when characteristic features evident. The disappearance parasite or inflammation, gliosis, and/or calcification suggest therapeutic response. initial experience CT scan has been greatly enhanced by MRI which currently imaging modality choice. This greater tissue contrast resolution its ability detect subtle changes parenchyma. Advanced techniques such as diffusion-weighted (DWI), perfusion (PI), MR angiography (MRA), spectroscopy (MRS) used improve sensitivity characterizing type, viability, burden parasites host Additionally, it possible primary those secondary treatment, some cases.