Resistance mechanisms in Campylobacter jejuni.

摘要: Campylobacter jejuni is a major cause of food-borne gastroenteritis worldwide. While mortality low, morbidity imparted by post-infectious sequelae such as Guillain-Barre syndrome, Reiter syndrome/reactive arthritis and irritable bowel syndrome significant. In addition, the economic cost high due to lost productivity. Food animals, particularly poultry, are main reservoirs C. jejuni. The over-use antibiotics in human population animal husbandry has led an increase antibiotic-resistant infections, with fluoroquinolones. This problematic because clinically indistinguishable from that caused other bacterial pathogens, illnesses usually treated empirically Since naturally transformable, acquisition additional genes imparting antibiotic resistance likely. Therefore, understanding mechanisms needed provide proper therapy both veterinary populations.