Computational Analysis of Displacement Forces Acting on Endografts Used to Treat Aortic Aneurysms

摘要: Endovascular repair has greatly reduced the perioperative morbidity and mortality of abdominal aortic aneurysm compared to open surgery (Zarins et al., J. Vasc. Surg 38(6): 1264–1272, 2003). However, endovascular stent-grafts are exposed a number clinical complications, such as endograft migration (i.e., loss positional stability), stent fractures endoleaks persistence blood flow into sac after device placement). These complications may result in life-threatening costly events growth, rupture, need for secondary procedures, life-long follow-up with imaging studies. Understanding biomechanical environment experienced by endografts vivo is critical factor improving their performance (Figueroa Endovasc. Ther 16(3):350–358, 2009; 284–294, 2009). The loads dependent on tortuosity size endograft, well hemodynamic state patient. fixation response determined factors mechanism (radial pressure vs. hooks barbs), amount “landing zone” area where can physically attach aorta), disease vessel wall at landing zone. purpose this study review most common associated thoracic aneurysms, provide summary art computational tools used perform patient-specific modeling dynamics.