Experimental Studies on the Repair of Wounds and Defects of the Trachea and Bronchi

摘要: SUMMARY Full-thickness segments of the trachea have been removed from dogs and defects bridged by glass or metal tubes. The tubes were tolerated well most animals. Examination tissue about these at intervals two weeks to 14 months following operation revealed that small islands rings new cartilage growing in granulation tissue. It is believed this develops fibroblasts 1 Several other types operative procedure carried out on dogs. observations made: 1) Longitudinal incisions dog's heal without residual deformity tracheal wall. Complete transverse division end-to-end suture results healing with rather marked stenosis neck whereas firm occurs much less evidence thoracic trachea. 2) Transplants patches wall, cm. square containing parts three cartilages successfully used fill similar size. These grafts appeared be equally whether taken same animal transplanted tracheas gradually disappeared transplants, finally being composed fibrous In animals did not change appearance others it was formed. 3) Segments entire trachea, long, which contained then replaced suture. had no respiratory difficulty after sacrificed end weeks. found healed histological examination tissues normal appearance. Similar transplants cervical became partly necrotic rapidly scar, contracture graft one another, both portions also scar those developed so within because obstruction.