Dielectric properties of mouse lymphocytes and erythrocytes

摘要: In order to study the effect of nucleus on dielectric behavior whole cell, permittivity (dielectric constant) and conductivity mouse lymphocytes erythrocytes were measured over a frequency range from 0.1 250 MHz. Erythrocytes (spherocytes) showed single dispersion, which was explained by single-shell model that is conducting sphere covered with thin insulating shell. On other hand, broad dispersion curve composed two subdispersions. The high-frequency subdispersion, not found for erythrocytes, assigned Maxwell-Wagner occupying about 65% total cell volume. Analysis lymphocyte carried out double-shell model, in shelled sphere, i.e., nucleus, incorporated into model. following electrical parameters consequently estimated; capacitance plasma membrane, 0.86 microF.cm-2; cytoplasm, 3.2 mS.cm-1; conductance nuclear envelope are, respectively, 0.62 microF.cm-2 15 S.cm-2, nucleoplasm are 52 13.5 mS.cm-1.