Radioactive mercury distribution in biological fluids and excretion in human subjects after inhalation of mercury vapor.

作者: M. George Cherian , John B. Hursh , Thomas W. Clarkson , Judi Allen

DOI: 10.1080/00039896.1978.10667318

关键词: PhysiologyUrinary systemBlood plasmaRenal functionUrineRadiochemistryWhole bloodChemistryInhalationExcretionMercury (element)

摘要: Abstract The distribution of mercury in red blood cells (RBCs) and plasma, its excretion urine feces are described five human subjects during the first 7 days following inhalation radioactive vapor. A major portion (98%) whole is initially accumulated RBCs transferred partly to plasma compartment until ratio about 2 within 20 hr. cumulative urinary fecal for 11.6% retained dose, closely related percent decline body burden mercury. There little correlation between either radioactivity mercury, or specific activities suggesting a mechanism other than direct glomerular filtration involved recently exposed These studies suggest that levels can be used as an index recent exposure, while may...

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