Study of Aldosterone Synthase Inhibition as an Add-On Therapy in Resistant Hypertension

作者: Adam D. Karns , Jacqueline M. Bral , Daniel Hartman , Thomas Peppard , Christoph Schumacher

DOI: 10.1111/JCH.12051

关键词: EplerenoneAldosteroneMedicineAldosterone synthasePlasma renin activityMineralocorticoid receptorAdrenal glandPlaceboBlood pressureEndocrinologyInternal medicine

摘要: Aldosterone inhibition with mineralcorticoid receptor antagonists (MRAs) is an effective treatment for resistant hypertension. Aldosterone synthase inhibitors (ASIs) are currently …

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