Human growth hormone: a complex of proteins

摘要: Publisher Summary This chapter discusses that the human growth hormone is a complex of proteins. Human stands apart from all other pituitary hormones when one considers amount present in gland. It amounts to 8 mg/gland as compared which are found microgram amounts. Using analytical and preparative techniques, it has been not single substance but mixture variants differing amino acid sequence, posttranslational modified forms, fragments. The focuses on experimental results support concept each forms can be separate with different physiological role only taken altogether account for often contradictory actions hormone. stimulated by two reports—the elegant gel electrophoresis technique, less effective inhibiting glucose uptake if recrystallized. electrophoretic approach makes apparent preparations heterogeneous, also contaminated proteinase readily produces hydrolytic products contributes heterogenity.