Exclusion of a Brain Lesion: Is Intravenous Contrast Administration Required after Normal Precontrast Magnetic Resonance Imaging?

摘要: Background No evidence-based guidelines are available for the administration of gadolinium-based contrast media to veterinary patients. Objective To investigate whether intravenous (IV) alters likelihood identifying a brain lesion in dogs and cats. Animals Four hundred eighty-seven client-owned animals referred investigation intracranial disease. Methods Two reviewers retrospectively analyzed precontrast transverse sagittal T1-weighted (T1W), T2-weighted, fluid-attenuated inversion recovery low-field MRI sequences from each patient presence clinically relevant lesion. All subsequently were reviewed same manner with additional access postcontrast T1W images. Results Of 487 studies, 312 judged be normal by 1 or both reviewers. Of these previously undetected was identified only 6 cases (1.9%) based on changes observed sequences. Final diagnoses included meningoencephalitis unknown origin (n = 1), feline infectious peritonitis neoplasia (n = 2). 4 had persistent neurological deficits suggestive an underlying Contrast enhancement 2 other considered falsely positive results further investigations. Conclusions Clinical Importance In patients examination MRI, subsequent IV is highly unlikely disclose unidentified lesion, calling into question routine patients. However, still should inflammatory neoplastic