Indoleamine 2,3 Dioxygenase-Dependent T Cell Suppression and Pregnancy
作者： Babak Baban , Phillip R. Chandler , Andrew L. Mellor
关键词: T cell 、 Andrology 、 Immune system 、 Gestation 、 Biology 、 Indoleamine 2,3-dioxygenase 、 Vivipary 、 Fetus 、 Pregnancy 、 Fetal tissue
摘要: Viviparity remains an immunological paradox despite increased knowledge of immuno-logical processes that occur during mammalian pregnancy. The maternal immune system protects both mother and fetus from invading pathogens gestation, but also has to maintain tolerance towards the fetus. Medawar proposed three ways in which this might be resolved: physical segregation fetal tissues, immunologic immaturity anergy (tolerance) alloantigens.1
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