Substrate stiffness regulates primary hepatocyte functions

作者: Vaishaali Natarajan , Eric J. Berglund , Dorothy X. Chen , Srivatsan Kidambi

DOI: 10.1039/C5RA15208A

关键词: Cytochrome P450Signal transductionHepatocyte nuclear factorsDownregulation and upregulationCell biologyBiochemistryTissue cultureConnexin 32HepatocyteExtracellular matrixChemistry

摘要: … to study the effect of varying stiffness on the phenotype of primary rat hepatocytes. PDMS is a … matrix stiffness will influence hepatocyte phenotype and function, and that hepatocytes will …

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