Distinct role of autophagy on angiogenesis: highlights on the effect of autophagy in endothelial lineage and progenitor cells.
作者： Mehdi Hassanpour , Aysa Rezabakhsh , Masoud Pezeshkian , Reza Rahbarghazi , Mohammad Nouri
DOI: 10.1186/S13287-018-1060-5
关键词: Autophagy 、 Biology 、 Angiogenesis 、 Context (language use) 、 Stem cell 、 Cell biology 、 Cell 、 Progenitor cell 、 Signal transduction 、 Intracellular
摘要: Autophagy plays a critical role in the dynamic growth of each cell through different conditions. It seems that this intracellular mechanism acts as two-edged sword against numerous insults. Previously, autophagy was described context activity and behavior, but little knowledge exists related to endothelial cells, progenitors, stem cells biology from tissues. Angiogenic behavior lineage various are touted an inevitable feature restoration damaged tissues organs. This capacity found be dictated by signaling pathway. review article highlights fundamental autophagic response function, dynamic, differentiation rate. elucidation mechanisms pro- and/or anti-angiogenic potential inside could help us modulate therapeutic post-transplantation.
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