Amyloid β-induced impairments in hippocampal synaptic plasticity are rescued by decreasing mitochondrial superoxide.

作者: T. Ma , C. A. Hoeffer , H. Wong , C. A. Massaad , P. Zhou

DOI: 10.1523/JNEUROSCI.6566-10.2011

关键词: Long-term potentiationSuperoxideSuperoxide dismutaseBiochemistryNADPH oxidaseMitoQCell biologyReactive oxygen speciesChemistryMitochondrial ROSMitochondrion

摘要: … Tg2576 mouse model of AD. In the current study, we explored whether AD-related LTP impairments … , we treated slices with Aβ and then stained them with MitoSOX to determine how …

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