Mechanisms of programmed cell death in the developing brain.
作者： Chia-Yi Kuan , Kevin A. Roth , Richard A. Flavell , Pasko Rakic
DOI: 10.1016/S0166-2236(00)01581-2
关键词: Neural cell 、 Nervous system 、 Programmed cell death 、 Biology 、 Apoptosis 、 Mechanism (biology) 、 Progenitor cell 、 Neuron 、 Neuroscience 、 Central nervous system
摘要: Programmed cell death (apoptosis) is an important mechanism that determines the size and shape of vertebrate nervous system. Recent gene-targeting studies have indicated homologs cell-death pathway in nematode Caenorhabditis elegans analogous functions apoptosis developing mammalian brain. However, epistatic genetic analysis has revealed progenitor cells during early embryonic development postmitotic neurons at later stage brain distinct roles mechanisms. These results provide new insight on significance neural development.
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sci-hub.se 参考文章(56)
Stanley J. Korsmeyer, BCL-2 gene family and the regulation of programmed cell death. Cancer Research. ,vol. 59, ,(1999)
Dimitra Thomaidou, Marina C. Mione, John F. R. Cavanagh, John G. Parnavelas, Apoptosis and its relation to the cell cycle in the developing cerebral cortex The Journal of Neuroscience. ,vol. 17, pp. 1075- 1085 ,(1997) , 10.1523/JNEUROSCI.17-03-01075.1997
Martin C. Raff, Social controls on cell survival and cell death Nature. ,vol. 356, pp. 397- 400 ,(1992) , 10.1038/356397A0
T.M Michaelidis, M Sendtner, J.D Cooper, M.S Airaksinen, B Holtmann, M Meyer, H Thoenen, Inactivation of bcl-2 Results in Progressive Degeneration of Motoneurons, Sympathetic and Sensory Neurons during Early Postnatal Development Neuron. ,vol. 17, pp. 75- 89 ,(1996) , 10.1016/S0896-6273(00)80282-2
Jie Yang, Xuesong Liu, Kapil Bhalla, Caryn Naekyung Kim, Ana Maria Ibrado, Jiyang Cai, Tsung-I Peng, Dean P Jones, Xiaodong Wang, Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked Science. ,vol. 275, pp. 1129- 1132 ,(1997) , 10.1126/SCIENCE.275.5303.1129
K. A. Roth, C.-Y. Kuan, T. F. Haydar, C. D'Sa-Eipper, K. S. Shindler, T. S. Zheng, K. Kuida, R. A. Flavell, P. Rakic, Epistatic and independent functions of Caspase-3 and Bcl-XL in developmental programmed cell death Proceedings of the National Academy of Sciences of the United States of America. ,vol. 97, pp. 466- 471 ,(2000) , 10.1073/PNAS.97.1.466
Chia-Yi Kuan, Derek D. Yang, Deborah R.Samanta Roy, Roger J. Davis, Pasko Rakic, Richard A. Flavell, The Jnk1 and Jnk2 Protein Kinases Are Required for Regional Specific Apoptosis during Early Brain Development Neuron. ,vol. 22, pp. 667- 676 ,(1999) , 10.1016/S0896-6273(00)80727-8
M. Narita, S. Shimizu, T. Ito, T. Chittenden, R. J. Lutz, H. Matsuda, Y. Tsujimoto, Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria Proceedings of the National Academy of Sciences of the United States of America. ,vol. 95, pp. 14681- 14686 ,(1998) , 10.1073/PNAS.95.25.14681
Thomas L Deckwerth, Jeffrey L Elliott, C.Michael Knudson, Eugene M Johnson, William D Snider, Stanley J Korsmeyer, BAX is required for neuronal death after trophic factor deprivation and during development Neuron. ,vol. 17, pp. 401- 411 ,(1996) , 10.1016/S0896-6273(00)80173-7
Kanaga Sabapathy, Wolfram Jochum, Konrad Hochedlinger, Lufen Chang, Michael Karin, Erwin F Wagner, Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2. Mechanisms of Development. ,vol. 89, pp. 115- 124 ,(1999) , 10.1016/S0925-4773(99)00213-0