The effects of Na4P2O7.10H2O addition on the mechanical properties of sintered Ca2P2O7 bioceramic

作者: Feng-Huei Lin , Jen-Ren Liaw , Min-Hsiung Hon , Cheng-Yi Wang

DOI: 10.1016/0254-0584(95)01541-8

关键词: Bone growthChemical engineeringFlexural strengthBiomaterialMaterials scienceBioceramicMetallurgyGrain growthMicrostructureCompressive strengthSintering

摘要: Abstract From the viewpoint of hard tissue response to implant materials, calcium phosphates are probably most compatible materials presently known. Thus, during last few years much attention has been paid hydroxyapatite and β-tricalcium phosphate as potential biomaterials for bone substitute. However, disadvantage all proposed ceramics is their low mechanical strength. Therefore, applicability these restricted non-stressed regions. The ultimate good implantation in skeleton reach full integration non-living with living bone. material could be used, a graft, itself resorbs or dissolves growth occurs, end result new remolded Ca 2 P O 7 one intermediate products mineralized crystal from amorphous phosphates. doped certain amount Na 4 · 10H was prepared developed material. In this study, used liquid phase sintering additive which expected improve process promote physiological bioresorbability. Compressive strength four-point bending were measured by Bionix 858 test system. At beginning, proportionally increased addition up 5 wt.%, but thereafter decreased. microstructure crystalline identification analyzed techniques scanning electron microscopy (SEM), probe micro-analysis (EPMA), transmission (TEM) X-ray diffraction (XRD). relationship between sintered bioceramics dopant given terms presence NaCa(PO 3 ) , grain abnormal coalescence while increased.

参考文章(8)
Christel P.A.T. Klein, K. de Groot, A.A. Drissen, H.B.M. van der Lubbe, Interaction of biodegradable β-whitlockite ceramics with bone tissue: An in vivo study Biomaterials. ,vol. 6, pp. 189- 192 ,(1985) , 10.1016/0142-9612(85)90008-0
Samuel I. Stupp, Jacqueline A. Hanson, Jo Ann Eurell, Glenn W. Ciegler, Ann Johnson, Organoapatites: Materials for artificial bone. III. Biological testing Journal of Biomedical Materials Research. ,vol. 27, pp. 301- 311 ,(1993) , 10.1002/JBM.820270304
Toshiaki Kitsugi, Takao Yamamuro, Takashi Nakamura, Seiya Kotani, Tadashi Kokubo, Hiroyasu Takeuchi, Four calcium phosphate ceramics as bone substitutes for non-weight-bearing Biomaterials. ,vol. 14, pp. 216- 224 ,(1993) , 10.1016/0142-9612(93)90026-X
Dur N. Yoon, Winfried J. Huppmann, Grain growth and densification during liquid phase sintering of W-Ni Acta Metallurgica. ,vol. 27, pp. 693- 698 ,(1979) , 10.1016/0001-6160(79)90020-8
C. P. A. T. Klein, A. A. Driessen, K. de Groot, A. van den Hooff, Biodegradation behavior of various calcium-phosphate materials in bone tissue Journal of Biomedical Materials Research. ,vol. 17, pp. 769- 784 ,(1983) , 10.1002/JBM.820170505
Feng-Huei Lin, Haw-Chang Liu, Ming-Hsiung Hon, Cheng-Yi Wang, Preparation and in vivo evaluation of a newly developed bioglass ceramic Journal of Biomedical Engineering. ,vol. 15, pp. 481- 486 ,(1993) , 10.1016/0141-5425(93)90063-5
Ralph E. Holmes, Robert W. Bucholz, Ann Carlton, Hydroxyapatite and tricalcium phosphate bone graft substitutes. Orthopedic Clinics of North America. ,vol. 18, pp. 323- 334 ,(1987) , 10.1016/S0030-5898(20)30395-3
John E. Ritter, Mechanical Behavior of Ceramics Springer Netherlands. pp. 191- 221 ,(1991) , 10.1007/978-94-011-3836-9_11