Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells.
作者： Hua Xiong , Zhi-Gang Zhang , Xiao-Qing Tian , Dan-Feng Sun , Qin-Chuan Liang
DOI: 10.1593/NEO.07971
关键词: Signal transduction 、 Cell cycle checkpoint 、 Janus kinase 2 、 Cancer research 、 Cell growth 、 Janus kinase 、 Cell biology 、 Biology 、 Cell cycle 、 Carcinogenesis 、 STAT protein
摘要: Abnormalities in the STAT3 pathway are involved in the oncogenesis of several cancers. However, the mechanism by which dysregulated STAT3 signaling contributes to the …
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doaj.org参考文章(45)
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