Cerebral correlates of explicit sequence learning

作者: Arnaud Destrebecqz , Philippe Peigneux , Steven Laureys , Christian Degueldre , Guy Del Fiore

DOI: 10.1016/S0926-6410(03)00053-3

关键词: Cerebral blood flowSequence learningCerebral cortexPrefrontal cortexAnterior cingulate cortexNeuroscienceCognitive psychologyCingulate cortexDissociation (neuropsychology)PsychologyImplicit learning

摘要: Using positron emission tomography (PET) and regional cerebral blood flow (rCBF) measurements, we investigated the correlates of consciousness in a sequence learning task through novel application Process Dissociation Procedure, behavioral paradigm that makes it possible to separately assess conscious unconscious contributions performance. Results show metabolic response anterior cingulate/mesial prefrontal cortex (ACC/MPFC) is exclusively specifically correlated with explicit component performance during recollection learned sequence. This suggests significant role for ACC/MPFC processing sequential material.

参考文章(38)
M S Mega, R C Cohenour, Akinetic mutism: disconnection of frontal-subcortical circuits Neuropsychiatry Neuropsychology and Behavioral Neurology. ,vol. 10, pp. 254- 259 ,(1997)
Alan Richardson-Klavehn, John M Gardiner, Rosalind I Java, None, Memory: Task dissociations, process dissociations and dissociations of consciousness Oxford University Press. ,(1996)
Gy�rgy N�meth, Katalin Heged�s, L�szl� Moln�r, Akinetic mutism associated with bicingular lesions: Clinicopathological and functional anatomical correlates European Archives of Psychiatry and Neurological Sciences. ,vol. 237, pp. 218- 222 ,(1988) , 10.1007/BF00449910
Peter A. Frensch, Michael A. Stadler, Handbook of implicit learning Sage Publications, Inc. ,(1998)
T Johnstone, Shanks, Implicit knowledge in sequential learning tasks In: Stadler, MA and Frensch, PA, (eds.) Handbook of Implicit Learning. (pp. 533-572). Sage: Thousand Oaks, CA. (1998). ,(1998)
Matthew Botvinick, Leigh E. Nystrom, Kate Fissell, Cameron S. Carter, Jonathan D. Cohen, Conflict monitoring versus selection-for-action in anterior cingulate cortex Nature. ,vol. 402, pp. 179- 181 ,(1999) , 10.1038/46035
Giulio Tononi, Gerald M Edelman, Consciousness and Complexity Science. ,vol. 282, pp. 1846- 1851 ,(1998) , 10.1126/SCIENCE.282.5395.1846
Chris D Frith, Uta Frith, Interacting Minds--A Biological Basis Science. ,vol. 286, pp. 1692- 1695 ,(1999) , 10.1126/SCIENCE.286.5445.1692
E. Koechlin, G. Corrado, P. Pietrini, J. Grafman, Dissociating the role of the medial and lateral anterior prefrontal cortex in human planning Proceedings of the National Academy of Sciences of the United States of America. ,vol. 97, pp. 7651- 7656 ,(2000) , 10.1073/PNAS.130177397
Howard J. Aizenstein, Angus W. MacDonald, V. Andrew Stenger, Robert D. Nebes, Jeris K. Larson, Stefan Ursu, Cameron S. Carter, Complementary Category Learning Systems Identified Using Event-Related Functional MRI Journal of Cognitive Neuroscience. ,vol. 12, pp. 977- 987 ,(2000) , 10.1162/08989290051137512