Advances in the Clinical Management of Cardiac Arrest

作者: Spyros G. Zakynthinos , Spyros D. Mentzelopoulos , Iosifinia Kolliantzaki

DOI: 10.2015/HC.V9I2.582

关键词: Cardiopulmonary resuscitationEpinephrineAnesthesiaMedicineShock (circulatory)Clinical researchHeart failureBeta-adrenergic blocking agentClinical deathHypothermia

摘要: Cardiac arrest constitutes an extremely life-threatening condition that inevitably and promptly results in death if left untreated. outcomes still remain very poor, especially when the presenting cardiac rhythm is nonshockable. Important, recent, clinical research has focused on quality of cardiopulmonary resuscitation (CPR), mechanical augmentation circulation during CPR, CPR drugs, therapeutic hypothermia. Chest compression depth at least 51 mm increases probability neurologically favorable survival. Despite initially promising results, a large effectiveness study failed to confirm efficacy circulation. Epinephrine finally been shown slightly improve functional outcome after out-of-hospital arrest, given early. In in-hospital 268 patients, addition vasopressin methylprednisolone administration hydrocortisone postresuscitation shock improved vasopressor-requiring arrest; however, corticosteroid needs be separately confirmed large, international trial. Lastly, preliminary human data may support conduct high trials evaluating beta adrenergic antagonists shockable arrest. The purpose this paper review these potentially important advances management

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