Immunological Classification of “Unclassifiable” Acute Leukemia

摘要: Cytochemical and immunological markers have helped to elucidate the ontogeny of hematopoietic cells improved subclassification acute leukemia (reviewed in Refs. 1–3). Nonetheless, a small fraction (5–10%) leukemias lack expression standard cytochemical no morphological features providing evidence for cell lineage (4). Such cases—usually referred as “acute unclassifiable leukemia” (AUL)—may reflect leukemic counterparts earliest stem cells. The development monoclonal antibodies (mAbs) which include earlier differentiation stages their reactivity may be helpful determining type affiliation such