Application of novel molecular marker to preparation of kit for diagnosis and prognosis of renal clear cell carcinoma

作者: Zhou Liyuan , Sun Xiwei , Wang Ping , Lu Yan , Liu Pengyuan

DOI:

关键词: Renal clear cell carcinomaMolecular markerRNA SequenceCancer researchTumor SampleMedicine

摘要: The invention discloses application of a novel molecular marker to the preparation kit for diagnosis and prognosis renal clear cell carcinoma. RNA sequence isshown in SEQ ID NO: 1 57. A mathematical model carcinoma is constructed by taking as base; high sensitivity good specificity, AUC can be 0.997, effect good. In addition, 57 tRF fragments serve markers classifying predicating survival periods patients; test data, tumor sample clustered into 3 subtypes according rRFs expression, survivorship curve analysis shows that have obvious difference. has excellent index characteristic, effectively applied diagnosis, classification carcinoma, clinical promotion values.

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