PMTCT from research to reality--results from a routine service.

作者: A.H. Coovadia , S.A. Jones , K.D. Bolton , M.F. Urban , G.G. Sherman

DOI: 10.7196/SAMJ.2556

关键词: Transmission (medicine)Population studyPublic healthTropical medicineMedicinePediatricsAcquired immunodeficiency syndrome (AIDS)Service (business)SidaNevirapine

摘要: Objectives. Assessment of the efficacy a prevention mother-to-child transmission (PMTCT) programme in routine service setting comparison to research environment. Design. Descriptive study over 13-month period utilising retrospective data obtained from hospital records complemented by prospective on sample patients enrolled determine an affordable HIV diagnostic protocol for infants. Setting. Routine PMTCT at Coronation Women and Children's Hospital (CWCH) situated Johannesburg affiliated University Witwatersrand. Subjects. Pregnant women known be infected who delivered CWCH 1 October 2001 31 2002. Outcome measures. The rate infants, which reflects nevirapine (NVP) delivery infant feeding practices, follow-up rates perinatally exposed children. Results. Of 8 221 deliveries, 234 (15%) occurred infected. 8.7% 6 weeks 8.9% 3 months age population verifies high NVP administration ability formula-feed their babies abstain breast-feeding. More than one-third infants never return more 70% are lost 4 age. Conclusions. low confirms this programme. HIVinfected children not being identified medical management as part follow-up. It is imperative that record keeping improved facilitate ongoing monitoring. S Afr Med J 2004; 94: 289-292.

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