Acute Q Fever in Adult Patients: Report on 63 Sporadic Cases in an Urban Area

摘要: We report here 63 sporadic urban cases of acute Q fever diagnosed in 1985-1997. Fifty-eight men and five women were included; the mean age (±SD) was 35.6 (±10.2) years. Twenty-six patients had pneumonia, 30 hepatitis, 7 a self-limited febrile illness. The most frequent radiological abnormalities lobar or segmental alveolar opacities involving right lower lobes. Chronic bronchitis significantly more among with pneumonic (P = .01). Thirty-two patients' illnesses through seroconversion, 12 by fourfold increase serum antibody titer, 19 initial high titers. Patients who initially received doxycycline shorter duration than those treated erythromycin other antibiotics .0001 P .0004, respectively). No patient died. Acute affects mainly men, frequently causing except chronic bronchitis, develop pneumonia. Hepatic presented pronounced increases liver function test values did fever. Treatment caused significant reduction