Preclinical toxicity and safety evaluation of Althaea officinalis L. extract as naturopathic medicine in common carp (Cyprinus carpio L.): Hematological and biochemical study

摘要: This study was conducted to evaluate the effects of marshmallow extract (Althaea officinalis L.) administration on blood cells and biochemical parameters carp liver. A total 150 carps (Cyprinus carpio, initial body mass 37.7 ± 4.4 g) were fed diets containing 0.0 (control diet), 2.5, 5, 10 g for 60 days. On days 30 60 experiment samples collected hematological liver enzyme activities—aspartate aminotransferase (AST), alanine amino transferase (ALT), lactate dehydrogenase (LDH), alkaline phosphatase (ALP)—were measured. No significant difference found (p > .05) in red (RBC); hemoglobin concentration (Hb); hematocrit (Htc); mean corpuscular volume (MCV); (MCH); or percentage neutrophils, basophils, eosinophils fish with different concentrations 60. However, white cell (WBC) count increased signifi...