Nutritional status of Malawian adults on antiretroviral therapy 1 year after supplementary feeding in the first 3 months of therapy.

作者: MacDonald Ndekha , Joep J. G. Van Oosterhout , Haroon Saloojee , John Pettifor , Mark Manary

DOI: 10.1111/J.1365-3156.2009.02322.X

关键词: Risk factorCohort studyBody mass indexPediatricsCost effectivenessOdds ratioMedicineRegimenSurgeryPopulationMortality rate

摘要: OBJECTIVE To test the hypothesis that individuals on antiretroviral therapy (ART) for 3 months with a greater body mass index (BMI) as result of supplementary feeding ready-to-use fortified spread would maintain higher BMI 9 after ended. METHODS Two cohorts wasted adults AIDS, 12 ART and either spread, an energy dense lipid paste; or corn/soy blended flour, were assessed clinical anthropometric status, quality life, adherence months. RESULTS 336 patients participated: 162 who had received 174 flour. stopping food supplements, both groups similar BMI, fat-free mass, hospitalization rate mortality. Binary logistic regression modelling showed lower CD4 count, older age at baseline associated risk death (odds ratio = 0.63, 95% CI 0.47-0.79). Adherence to regimen life in cohorts. CONCLUSION While can ameliorate established factor mortality, this effect is sustained only during time intervention. Supplementary longer than should be investigated.

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