作者: H. P. Schultheiss , M. Noutsias , U. Kühl , D. Lassner , U. Gross
DOI: 10.1007/S00108-005-1483-9
关键词: Gene mutation 、 Implantable defibrillator 、 Cardiomyopathy 、 Medicine 、 Cardiology 、 Amiodarone 、 Familial dilated cardiomyopathy 、 Internal medicine 、 Disease 、 Heart failure 、 Sudden cardiac death
摘要: Cardiomyopathies are common causes of heart failure and sudden cardiac death. According to the WHO classification, "specific" cardiomyopathies differentiated from "idiopathic" cardiomyopathies. Thus, this classification is primarily based on pathophysiological characteristics. The diagnostic spectrum in comprises entire non-invasive invasive cardiological examination techniques. exact verification certain necessitates additionally investigations. For example, immunohistological molecular biological investigations endomyocardial biopsies may confirm inflammatory cardiomyopathy, which often induced by viruses. Several studies have shown that specific immunomodulatory treatment options can halt progressive course disease. gene mutations been identified genetic/familial dilated cardiomyopathy. First-degree relatives should be screened for early stages. Primary prevention death shows increasing superiority implantable defibrillator compared with pharmacological approaches (i.e. amiodarone).