Coupling agents for radiolabeled antibody fragments
作者： Robert A Nicolotti , Richard Dean
DOI: 10.1016/0883-2897(88)90174-2
关键词: Combinatorial chemistry 、 Maleimide 、 Amine gas treating 、 Coupling (electronics) 、 Metal ions in aqueous solution 、 Stereochemistry 、 Molecule 、 Chelation 、 Moiety 、 Chemistry 、 Bifunctional
摘要: Bifunctional coupling agent for joining radionuclide metal ions to biologically useful molecules, including antibody Fab' fragments are disclosed. The agents contain a maleimide moiety and paramagnetic or chelating moiety. can be used selectively bind free sulfhydryl groups, amine groups.
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