Decellularized vascular prostheses resistant to thrombus occlusion and immunologic rejection

作者: Alan B. Lumsden , Changyi Chen

DOI:

关键词: Mechanical strengthMaterials scienceStructural integrityOcclusionAneurysm ruptureDecellularizationVascular stentThrombusBiomedical engineeringSurgery

摘要: The present invention relates to decellularized vascular prostheses that are resistant thrombus occlusion and have a low level of immunogenicity. denuded cells, coated with an anti-thrombogenic agent growth factor promotes recellularization further reduces the high mechanical strength, resist aneurysm rupture, allow for secure surgical sutures while maintaining structural integrity. provides blood vessels, valves or portions vessels containing valves. is also useful coating synthetic stents.

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