Iron Oxide Nanoparticles Induce Dopaminergic Damage: In vitro Pathways and In Vivo Imaging Reveals Mechanism of Neuronal Damage

作者: Syed Z. Imam , Susan M. Lantz-McPeak , Elvis Cuevas , Hector Rosas-Hernandez , Serguei Liachenko

DOI: 10.1007/S12035-015-9259-2

关键词: In vivoDopamineNeurotoxicityMitochondrionBiophysicsChemistryBiochemistryDopaminergicNeurochemicalOxidative stressReactive oxygen species

摘要: … dependent increase in reactive oxygen species (ROS) were observed … The supernatants were used for Western blot analysis of … caspase 3/7 activation, thereby contributing to apoptosis. …

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